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Childhood Solid Tumor Network
St. Jude Cloud
Data Resource:  St. Jude Cloud
Point of Contact:  
Clay McLeod ; Jinghui Zhang,  
Project

About This Dataset
The Childhood Solid Tumor Network (CSTN) offers the world's largest and most comprehensive collection of scientific resources for researchers studying pediatric solid tumors and related biology. Childhood solid tumors are often difficult to study and treat because they are rare and originate in the complex biological context of developing organs. CSTN was established to disseminate resources and data that have been developed at St. Jude Children's Research Hospital, with the aim of stimulating basic research and speeding translation to the clinic. The effort was launched in 2013 by Howard Hughes Medical Institute investigator Michael Dyer, PhD, of St. Jude Developmental Neurobiology, and Alberto Pappo, MD, of St. Jude Oncology.
Core Data Elements
Number of Cases
305
Case Sex
Female (139); Male (162); Not Reported (4)
Case Age At Diagnosis
0 to 4 years (95); 5 to 9 years (22); 10 to 14 years (36); 15 to 19 years (33); 20 to 24 years (9); Pediatric and Young Adult (<40 years) (110)
Case Race
American Indian or Alaska Native (2); Asian (2); Black or African American (40); More Than One Race (8); Other (2); White (130); Not Reported (121)
Case Ethnicity
Hispanic or Latino (21); Not Hispanic or Latino (163); Not Reported (121)
Case Disease Diagnosis
Adrenocoritcal Carcinoma (2); Clear Cell Sarcoma (2); Desmoplastic Small Round Cell Tumor (7); Epithelioid Sarcoma (3); Ewing Sarcoma (13); Fibromyxoid Sarcoma (1); Fibrosarcoma (2); Gastrointestinal Stromal Tumor (2); Germ Cell Tumor (1); Hepatoblastoma (2); High Grade Sarcoma;Undifferentiated Round Cell Sarcoma (1); Infantile Fibrosarcoma (1); Malignant Rhabdoid Tumor (3); Melanoma (4); Neuroblastoma (17); Osteosarcoma (39); Papillary Thyroid Cancer (1); Retinoblastoma (65); Rhabdoid Tumor (2); Rhabdoid Tumor;Melanoma (1); Rhabdomyosarcoma (29); Sarcoma (1); Spindle Cell Sarcoma (2); Synovial Sarcoma (2); Undifferentiated Embryonal Sarcoma Of The Liver (1); Undifferentiated Round Cell Sarcoma (1); Wilms Tumor (30); Not Reported (70)
Case Tumor Site
Not Reported (305)
Number of Samples
778
Sample Assay Method
RNA Sequencing (118); Whole Exome Sequencing (600); Whole Genome Sequencing (60)
Sample Is Xenograft
Yes (290)
Additional Data Elements
DATA REPOSITORY
Grant Information
P30CA021765
Cancer Center Support Grant (CCSG)
R01CA168875
Molecular Targeted Therapy for Retinoblastoma
R01CA219686
Novel Therapeutic Approaches for the Treatment of Rhabdomyosarcoma
Published In
https://doi.org/10.1038/nature23647
SAMPLE TYPE
Autopsy (24);  
Diagnosis (209);  
Germline (201);  
Metastasis (11);  
Relapse (43);  
Xenograft (290);  
Charts
Male (162); Female (139); Not Reported (4)
162Male